A clinical trial developed in Spain selected among the studies that will change Medicine in the world
The journal Nature Medicine has selected 11 clinical trials whose results are expected with great expectation by the international scientific community for the coming years.
January 30, 2023. 10:57 am
The PREDIMED Plus study is a clinical trial developed in Spain for the prevention of cardiovascular diseases based on an intervention with the Mediterranean Diet. He himself is among the studies that will change medicine in the world, according to Nature Medicine.
Specifically, the journal Nature Medicine has selected 11 clinical trials whose results are expected with great expectation by the international scientific community in the coming years.
The selected trials are being carried out in various parts of the world, from the United States, through different European countries, to Australia. Most of them try to clarify the role of certain drugs (some new) for the treatment of different pathologies. This is the case of Parkinson’s disease or Alzheimer’s disease. However, others deal with the early detection of cervical cancer in women vaccinated against the human papillomavirus, or the effectiveness of vaccines against COVID-19 in patients affected by the human immunodeficiency virus.
Studies that will change Medicine in the world
Among the trials that will change Medicine in the world, only the PREDIMED-Plus study refers to assessing the importance of lifestyle on disease prevention. PREDIMED-Plus is a trial conducted with the participation of more than 6,800 men and women aged 55 to 75 years. All of them with overweight or obesity and metabolic syndrome.
The project is promoted by the CIBER Department of Physiopathology of Obesity and Nutrition (CIBEROBN), of the Carlos III Health Institute. Its objective is to determine the effects of an intensive weight loss intervention based on a traditional hypocaloric Mediterranean diet. All this including the promotion of physical activity and behavioral support on the appearance of new events of cardiovascular disease and mortality.
Also, It will shed light on the importance of losing weight in the long term (through a hypocaloric diet and physical exercise) on different pathologies. Among them, it stands out: the incidence of obesity; diabetes; some types of cancer; dementia of different origins and many other diseases associated with obesity and metabolic syndrome; as well as its potential effect on quality or life expectancy and the mechanisms involved.
Jordi Salas Salvadó is a CIBEROBN researcher at the IISPV and one of the coordinators of PREDIMED Plus. According to the same “the international community is awaiting the results with great expectation. No one has yet shown that weight loss, achieved with a healthy diet and physical exercise and maintained over time, reduces the possibility of suffering a myocardial infarction. Even cerebral embolism or mortality from these causes”.
