Health

A sea sponge and two bacteria could hold the key to developing a medicine against covid

researchers from the University of British Columbia (UCB) in Canada announced Monday that they have identified 26 naturally occurring compounds that prevent the SARC-CoV-2 virus, which causes COVID-19infect human cells, which can create medicines against disease.

Scientists from UCB, in western Canada, published in the medical journal Antiviral Research that after investigating more than 350 natural compounds, they have identified the 26 that prevent the COVID-19 virus from reproducing in the human body.

The co-author of the study, the Mexican scientist Jimena Pérez-Vargas Obregón, told EFE that of these 26, three are especially effective in blocking the virus “and can also block the latest variants.”

Viral structure.  Viral particle is made up of a nucleus of nucleic acid (DNA or RNA) surrounded by a protein coat.  Conceptual illustrative virus.  3D illustration.Viral,Conceptual,of,a,covid-19, coronavirus, virus, influenza, norovirus, rotavirus, HIV, AIDS, sars, chikungunya, rhinovirus, variola, rubella, poliovirus, herpes, Influenza virus, RNA virus, paramyxovirus , 3D illustration, disease, infection, antivirus, epidemic, pandemic, biology, genetic, health, microbiology, microscopic, organic, science, research, infectious, transmission, respiratory infections, respiratory disease, vaccines, pneumonia, prevention, virions, viral pneumonia , respiratory syncytial virus, mutation, infectious agent, replicates, cells, organism, virology, immune, pathogen

The UCB associate researcher explained that the particularity of at least two of these compounds is that “they do not act against the virus but rather against a tool that the virus uses” to attack cellsso they are effective against the various variants.

The three most effective compounds are allotaketal C, from a marine sponge; bafilomycin D, from a marine bacterium; and holyrine A, also produced by a marine bacteria.

People undergoing coronavirus tests in Xian, China

The researchers soaked cells from human lungs with these compounds and infected them with SARS-CoV-2 to discover those that blocked the reproduction mechanism of the virus.

Pérez-Vargas Obregón, who studied Chemistry at the National Autonomous University of Mexico (UNAM) and later obtained a doctorate in Biochemical Sciences at the UNAM Institute of Biotechnology, warned that the discovery is only the beginning of a path that could lead to the production of medicines that combat the infection.

The UCB research team is now in the process of synthesizing the discovered compounds in the laboratory, in order to produce them without having to extract them from the organisms that produce them naturally.

Once synthesized, the researchers will carry out animal tests to demonstrate the effectiveness of the compounds in blocking the virus in large organisms.

Several people walk through the Beijing International Airport, in China, this Wednesday.  China has reduced the quarantine period for foreign arrivals with seven days in a government-run center and three days in house arrest

These two phases will take approximately one year, said the Mexican researcher.

Once the preclinical trials are complete, the UCB researchers will have to partner with another group to carry out clinic tests with humans.

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