hospital of alicante And elchetheir focus is on the province Fights antibiotic-resistant superbugsAlthough Most have been estimated by microbiology laboratory Doctor Balmis, who is in charge of Mass sequencing of patient samples from nine out of ten public health departments, A total of 1.6 million patients.
Connected
like this Ministry of Health It has been designated as a provincial reference. complete the task andElche Hospital, which detects antibiotic-resistant microorganisms tailored to its area, Composed of approximately 175,000 users.
are superbugs Strains of bacteria, viruses, parasites and fungi are resistant to most antibiotics and Medicines used to treat infections The cause is. They include resistant bacteria that can cause pneumonia, urinary tract or skin infections. 80% dishes Antibiotic medicines They leave the health center half the time your prescription is inappropriateAccording to Spanish Society of Family and Community Medicine (Semphic).
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The World Health Organization (WHO) has warned that if it is not stopped, bacteria will become resistant to antibiotics. There will be more deaths in the world in the year 2050 cancer, consumption rate of antimicrobial There is a real problem in our environment that is becoming increasingly worrying as it becomes more difficult to treat infections efficiently. The spread of bacteria with antibiotic-resistant genes.
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The direct consequences can be serious and include increased mortality (Resistant bacteria are responsible for 33,000 deaths per year in Europe, 4,000 of which are in Spain), long hospital stayThe Loss of protection for patients undergoing surgical intervention or immunosuppression And this Increase in health expenditure. Other than this, 10% patients admitted to hospitals Suffer from infections caused by antibiotic-resistant bacteria. A quarter of them die.
Superbacteria, hidden danger
this is because in the last decadesmainly due to Indiscriminate or inappropriate use of antibioticsbeen there Progressive appearance of bacteria resistant to the action of these drugs. “Antibiotic resistance is developing One of the biggest public health problems that needs to be addressed At the present time,” emphasizes Dr. Juan Carlos Rodríguez, head of the center’s microbiology service.
“The development of resistance to antibiotics is one of the biggest public health problems that must be faced at present.”
Dr. Juan Carlos Rodriguez. Head of Microbiology Service at Doctor Balmis Hospital in Alicante
In this context, this service of Doctor Balmis General University Hospital Establishes itself as a leading laboratory in the province of Alicante In various microbiological monitoring processes, e.g. Early detection and molecular diagnosis pathogens or microorganisms Resistant to antibiotics.
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this centerleads in spain, from A Swedish invention, A Research in which European countries are working to speed up patient diagnosis And sometimes reduce it to four hours compared to the required 72 hours, This means applying bombardments of antibiotics to stop disease, without knowing well which drug will work and what consequences it might have.
in network
For all this, Ministry of Health has nominated This year in the center service provincial reference (specifically, level 2 laboratory)Network of laboratories for surveillance of resistant microorganisms (Redlabra)which means it is They have been trained to receive and analyze samples from hospitals that make up Level 1, which are nine out of ten public departments in the province, through large-scale sequencing.With the exception of the General University Hospital of Elche, which sequences samples in its health sector.
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a decision that is well known Coinciding with World Antibiotic Awareness Week and European Day for the Judicious Use of Antibiotics, International campaigns that aim to raise awareness among the population about the responsible and reasonable use of these medicines in order to preserve the effectiveness of existing medicines and reduce the impact of this problem on the health of people and animals.
The fight against superbacteria infections is led by Alicante
Dr. Balmis, head of microbiology, confirmed that this designation has been given to him Your service is highly regarded” and shows that we perform specialized and highly complex work. It requires infrastructure, technical capacity, scientific-technical background… In this sense, We have high technology, four huge sequencing instruments, two classic and two third generationSome? accessible to very few people “Hospitals of Spain.”
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this was possible thanks Synergy between Microbiology Service and Institute of Health and Biomedical Research of Alicante (Isabiel). The germination of this collaborative work occurred during the COVID-19 pandemic, which allowed a symbiosis between It will be assumed that PCR tests will be conducted in 17 hospitals in the province, both public and private., With the advent of new coronavirus variants, it was also the provincial reference center for analyzing samples.
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When a multi-resistant bacteria is detected in the province’s hospitalsFor example, after analyzing a sample from a patient with a urinary infection, It is sent to the central laboratory of Doctor Balmis HospitalWhere complete genome sequencing Bacteria multi-resistant to antibiotics. result after It is sent to the Fisabio laboratory in Valencia, which acts as a node for the Valencian Community. and with the interlocutor Carlos III Health Institute. This is what this monitoring work involves.
Superbacteria, hidden danger
And What is the use of this indexing? Multiresistant bacteria? As Dr. Rodriguez explains, “It is It is necessary to know how resistant strains are distributed, when they appear or disappear, what types of growth…Knowledge of resistance and its dissemination is the first step Important in the fight against this serious problem,
“It is essential to know how resistant strains are distributed, when they appear or disappear, which types grow… Knowledge of resistance and its spread is an important first step in the fight against this serious problem “
Dr. Juan Carlos Rodriguez. Head of Microbiology Service at Doctor Balmis Hospital in Alicante
Surveillance and data exchange of this national laboratory network, RedLabRA, provides information needed to “establish therapeutic guidelines, infection control policies”. Appropriate antibiotic stewardship programs, public health interventions, as well as priorities in the development of new treatments and vaccines, among other actions,” he highlighted. RedLabRA is part of the National Plan against Antibiotic Resistance (PRAN), a strategic plan approved by the Interterritorial Council of National Health Systems at the request of the European Union.
Antibiotic resistance: rising deaths and a global problem
For its part, in 2015 a team of researchers of General University Hospital of Elche A test has been developed to optimize the treatment of infections caused by bacteria multi-resistant to antibiotics Previous Generation. A test with a blood sample to “rapidly” detect and classify the main enzymes involved in antibiotic resistance. Work in which Dr. Rodriguez also participated.
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