Medicines with which you should not mix coffee

according to the report I study coffee consumption habits in Spain Created by Café Nouvelle 70% of Spaniards over 18 drink coffee every day, The average is 2.2 cups per day and the preferred location is home (61%).

This steaming drink provides the energy you need to kick start your daily routine. Additionally, it is associated with lower risk of diseases and better physical performance. It is a good option to add it to your glass for weight loss as it only contains 5 calories per cup If you take it alone. Caffeine also appears to activate metabolism and fat burning.

However, mix coffee and medicine This is not always the most recommended. In general, you should always take the tablets with water. Since anything else can change the effect on your body. -It is worth paying special attention to those treating cholesterol, calcium blockers or certain medications that regulate the immune system, you should never combine them with grapefruit juice due to its adverse effects.

Caffeine can alter the effects of medications or cause serious side effects. As a 2021 study warned, coffee may contribute to the prevention of inflammatory diseases and diseases related to oxidative stress. Consume up to 400 mg per day (1-4 cups daily) is considered safe. However, the time interval between drinking your cup and taking certain medicines should be kept in mind to avoid interactions.

The Health and Drug Organization has warned to pay special attention to the following medicines.


Ephedrine is a stimulant stimulates the nervous system, It is included as a decongestant and bronchodilator to treat respiratory problems. It is also used to treat low blood pressure, narcolepsy, menstrual problems and others.

Because caffeine is a stimulant, Mixing ephedrine with coffee may pose health risks Such as high blood pressure, heart attack, stroke or seizures, the Mayo Clinic reports.

diabetes medicines

In some people, Coffee can increase blood sugar, Which possibly counteracts the effects of antidiabetic drugs. If you are diabetic, the organization says the dosage of your medications may need to be modified to take these effects into account.

For some people with diabetes, about 200 milligrams of caffeine, or one or more 240 ml black coffeeMayo Clinic experts say it can cause side effects.


Theophylline is used Treat asthma, bronchitis, emphysema And other diseases that are accompanied by difficulty breathing and wheezing. The drug works by relaxing the muscles, opening the airways, and improving the lungs’ response to irritants.

Caffeine has similar effects on the body as theophylline. Combination of both can increase the effect of the medicineas well as its side effects, which include nausea and heartburn.


Phenothiazines are a group of drugs used to treat mental disorders such as schizophrenia and other forms of psychosis.

The tannins in coffee can bind with these medications and prevent the body from doing so absorb them with the same efficiency, This interaction is most likely to occur if coffee is consumed within 1 to 2 hours of taking the medication.

tricyclic antidepressants

These depression medications include amitriptyline and imipramine. They work by increasing levels of the neurotransmitters norepinephrine and serotonin and inhibiting the neurotransmitter acetylcholine.

However, the association reports, certain compounds in coffee may interfere with this process by binding to medications and limiting the amount that can be absorbed by the body.
That’s why they recommend Avoid coffee for 1 to 2 hours after taking tricyclic antidepressants To ensure its effectiveness.

anti asthma

Beta-adrenergic agonists are used to treat asthma and include albuterol, metaproterenol, isoproterenol. They work by relaxing the muscles around the airways and may also have side effects. anxiety, tremors, palpitations, or increased heart rate Which can get spoiled due to the effect of caffeine.

Apart from the above, you can also drink coffee Interact with Vitamin Supplements,

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