Fortune often plays an outstanding role in the progress of medicine, as the discovery of penicillin has shown us. Now a ray of hope has been seen in the fight against malaria with a completely accidental discoveryIn one experiment, a colony of mosquitoes would not develop malaria parasites due to the presence of TC1 bacteria that are commonly found in nature.
TC1 bacterium, commonly found in nature, inhibits the growth of the malarial parasite in the mosquito’s intestine
Researchers say this bacterium could be a new tool to combat one of the world’s oldest diseases and one that causes more than 600,000 deaths annually. Therefore, trials are underway to assess its safety in the real world.
Scientists at a research center in Spain run by the pharmaceutical company GSK found that the colony of mosquitoes they used for drug development stopped transmitting malaria. “Infection rates of mosquitoes began to decline and by the end of the year, mosquitoes would no longer be infected with the malaria parasite”he declared. Janeth Rodrigues, director of research programs.
hormone molecule
The disappearance of the virus in mosquitoes was due to a specific type of bacteria, TC1 inhibited the growth of malarial parasites in the intestine of insects. “Once it settles in a mosquito, it stays there for life. Therefore, we found that the TC1 bacterium was responsible for reducing transmission in insects,” Rodrigues said.
The bacteria work by secreting a small molecule, known as a hormone.He Inhibits an early stage of development of the malarial parasite in the mosquito’s intestine
Plus, new data published in the journal Science showed that the bacterium can reduce a mosquito’s parasite load by up to 73 percent. The bacteria work by secreting a small molecule, known as a hormone.He Inhibits an early stage of development of the malarial parasite in the mosquito’s intestine,
GSK scientists together with Hopkins University find out Mosquito can ingest the hormone orally, Absorb it through your cuticles if mixed with sugar, or on contact. This opens up the possibility of treating surfaces in areas where insects rest with the active compound.
mosquito net
Further tests are now underway at a contained field research facility called Mosquito ball in Burkina Faso To assess how effective and safe it would be to use Harmen on a large scale in the real world. The hope is that developing this bacteria-based intervention into a drug could give scientists a more effective tool for one of the world’s oldest and deadliest diseases in the short term.
Further trials are underway at a contained field research facility called Mosquitosphere in Burkina Faso.
Malaria kills about 620,000 people per year, often children under the age of five. Vaccines have already been developed, but are still in the early stages of implementation in Africa. Gareth Jenkins, of the charity Malaria No More, described the new finding as promising. “Malaria kills a child every minute. Significant progress has been made in reducing the global burden of malaria, but we need new and innovative tools in our arsenal to get us back on track. With a concerted series of innovations, it is possible to eliminate the menace of malaria in our lives”, the researcher stressed.