They detect a breakdown in the immune system that causes persistent Covid.

Nearly four years into the pandemic, scientists continue to study and discover new aspects of the virus that has paralyzed the world and left millions of deaths in its wake. Now, a team of scientists led by the University Hospital of Zurich has discovered a new benefit of the coronavirus that could be a major advance in the fight against the disease: failure of our immune system what causes Long Covid.

He complement system This is one of the most important parts of the immune system and is where source this syndrome. This international study has identified a number of biomarkers that may improve disease diagnosis and pharmacological approaches.

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According to the results published today in the journal The scienceThis change in the balance of the complement system causes the immune system to attack endothelial cells, which line the inner layer of blood vessels. This reaction causes inflammation of the endothelium and promotes the formation blood clots, which reactivates the complement system itself. The problem that arises is that it ends up creating Feedback it’s hard to get out. According to the authors of the study, published in the journal Sciencie, “early cardiovascular screening of patients with persistent Covid should be considered.”

The study analyzed 6,596 proteins in the blood of 152 people, of whom 113 became ill in the first year of the pandemic and 39 were healthy volunteers. Among those who contracted the infection, 50% still had symptoms a month after initial diagnosis and were therefore classified as persistent Covid cases. In these patients, scientists found excessive activation of the complement system from the acute phase of infection

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persistent Covid symptoms They may fluctuate or remain constant over time, worsen due to greater physical or mental effort, and even limit functional abilities or cognitive abilities. The symptoms are very diverse and are grouped into several groups, according to the Ministry of Health:

• General: fatigue, general malaise, pain in muscles and joints, dizziness, increased body temperature, sleep disturbances.
• Respiratory system: cough, feeling of shortness of breath.
• Digestive Aids: diarrhea, loss of appetite, stomach pain.
• Dermatological: rash, hair loss, weak nails.
• Neurological: headache, brain fog, difficulty concentrating, loss of taste and smell, paresthesia and mood disturbances.
• Ears, eyes, throat: difficulty swallowing, ringing in the ears, dry eyes, or conjunctivitis.
• The cardiovascular system: heartbeat, change in blood pressure.

Campaign vaccination against COVID-19 in Spain It began at the end of December 2020, after the European Medicines Agency (EMA) approved the first vaccines. The vaccination strategy was developed according to a prioritization scheme initially targeting the most vulnerable groups and those at greatest risk of contracting the virus, such as health care staff and care center residents.

Spain has used vaccines such as Pfizer-BioNTek, modern, AstraZeneca-Oxford and Jansen (Johnson & Johnson), among others that have received appropriate approval. Logistics and distribution of vaccines are carried out centrally, with periodic deliveries to autonomous communities, which in turn organize the administration of doses in accordance with the vaccination plan established at the national level.