Two Key Indicators of Cognitive Decline According to Latest Research

Recent study shed light on factors this may be fundamental for early detection mild cognitive impairment (DCL) and Alzheimer’s disease (EA). In a context where dementia affects more and more people, these results may mean difference significant in struggle against these pathology.


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About a third elderly people die with Alzheimer’s disease or other form dementiamaking these diseases the seventh leading cause death at the global level. For this reason, the World Health Organization (WHO) has emphasized that they are priority in the area public health.

The importance of this study lies in its ability to identify early signs this may go unnoticed at first clinical examinations. Next we will tell you what it is indicators from cognitive impairment.

Research results

A recent study led by Kironsalud in collaboration with Roche Pharmashed light on some factors this may be critical in identifying mild cognitive impairment (MCI) and disease Alzheimer’s disease (EA).

This study focused on data collected between 2007 And 2022 more than 2000 patients who came for consultations on problems memory or cognition V hospitals from Quironsaluda in Madrid.

According to the most notable results of this observational studyintegrate factors such as age, apathy, anxiety And educational level in prognostic models may contribute to early detection cognitive impairment.

Cognitive decline may occur over time if memory is not trained.

What are the key indicators of cognitive decline, according to research?

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This highlights importance incorporating these elements to promote both early detection how is he care in cases Alzheimer’s disease.

In this studyVarious variables have been included to assess cognitive impairment, such as Global Deterioration Scale (GDS), which measures cognitive ability, and Neuropsychiatric Questionnaire (NPI), which examines 12 relevant neuropsychiatric symptoms observed over the past month. Moreover, they were considered demographic factors.

results The GDS indicated that as a result of its assessments, 623 people were classified as cognitively healthy644 s DCL and 966 s advisor. It should be noted that the group diagnosed with AD was older age and the one who less knowledge told about his condition.

Age, apathy and education level

Doctor Rafael ArroyoHead of the Department of Neurology at the Olimpia and Quironsalud Madrid and Ruber Juan Bravo University Hospitals, emphasizes that “ age And apathy look like risk factors in development DCL And advisor. On the contrary, high educational level acts like protective factorhelping to mitigate the deterioration of the condition.”

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What are the key indicators of cognitive decline, according to research?

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As is already known, family history represent a significant risk factor in the development of the disease. Alzheimer’s disease. Therefore, the expert emphasizes that future research should focus on collection systematic and standardized of these datain order to improve accuracy And utility belonging forecasting tools.

Arroyo also emphasizes that these data allowed us to confirm an important aspect known as “cognitive reserve“, which is related to educational level people. The greater the cognitive reserve, the lower probability suffer cognitive impairment.



This information in no way replaces a doctor’s diagnosis or prescription. It is important to consult a specialist when symptoms appear and under no circumstances self-medicate.

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