Children of mothers with Alzheimer’s disease are at greater risk of developing the disease

Alzheimer’s disease is a specific brain disease that causes memory loss and problems with behavior and thinking. It usually appears after age 65, although the first clinical symptoms may appear 15 or 20 years earlier.

According to the Spanish Society of Neurology (SEN), in our country alone, about a million people suffer from Alzheimer’s disease and It is often difficult to take action early on. because of how difficult it is to predict risk.

Now a new study conducted by researchers from Mass General Brigham (USA) and published in JAMA Neurology suggests that a person inherits the risk of Alzheimer’s disease from their mother or father. affects the risk of biological changes in the brain which lead to disease.

To reach this conclusion, they analyzed the data 4400 people from 65 to 85 years oldparticipants in the Anti-Amyloid Treatment Study for Asymptomatic Alzheimer’s Disease (A4).

Participants were asked whether their parents had experienced symptoms of memory loss and at what point in their life did they appearand whether they had ever received a diagnosis of Alzheimer’s disease. They also underwent a PET (positron emission tomography) scan to quantify the amount of defective beta-amyloid proteins in the brain, which is thought to basic physiological sign Alzheimer’s disease.

“Our study found that if participants had a maternal family history, higher levels of amyloid” says senior author Hyun-Sik Yang, a neuroscientist at Mass General Brigham and a behavioral neurologist in the Department of Cognitive and Behavioral Sciences.

In short, studies have shown greater amyloid accumulation. if the person’s mother had symptoms of Alzheimer’s disease at any age or in both parents compared with those who developed symptoms of Alzheimer’s disease only in the father.