Metformin, a possible treatment for aging

Throughout history, people have searched for a cure or a way to prevent aging. Now the efforts may bear fruit: a popular drug for the treatment of type 2 diabetes will appear: metformina drug that appears on the list of essential medicines World Health Organization (WHO), for a long time. The effect of this drug is associated with controlling the level of sugar produced by the liver and increasing the body’s response to insulin.

However, in addition to these effects, the molecule metformin may help delay aging, so it has been studied for many years to determine its properties in this regard. This year Clinical University of Navarra

was added to existing research projects to see if the drug could serve anti-aging treatment towards chronic obstructive pulmonary disease (COPD).

“Metformin helps maintain the stability of cellular proteins, improve mitochondrial function and stability of genetic material, or facilitate intracellular communication.”

So the doctor Juan Pablo de Torresco-director Department of Pulmonology, noted that metformin “helps maintain the stability of cellular proteins, improve mitochondrial function and the stability of genetic material, or facilitate intracellular communication.” Additionally, it may help stop loss pulmonary functionone of the main pathologies accelerated aging.

Other studies conducted in this context reportedly date back to 2014. Independent. This year a group of researchers from Cardiff University compared cardiovascular risk and mortality among patients taking metforminpeople who have taken other medications for treatment diabetes and people without diabetes.

However, they came to the conclusion that patients taking metformin With monotherapy, they had a longer life expectancy than the other two previous groups, by 38% and 15%, respectively. Thus, it has been shown that the drug can have a positive effect on patients without diabetes

.

Subsequently, other studies showed that it also had an effect on reducing the occurrence of diseases associated with aging. Some of them are cardiovascular diseases for example, heart failure or coronary heart disease, or neurodegenerativesuch as Alzheimer’s, Parkinson’s and cancer.

Last year 2023, researchers from Hong Kong Medical University They also concluded that metformin promotes healthy aging by comparing biological markers aging among patients metformin and other medicines for diabetes.

The advantage of the new clinical trials is that metformin is a very affordable drug and there are many other studies already done on its effectiveness.

New clinical trials have the advantage that metformin This is a very affordable drug and there have already been many other studies done on its effectiveness, so this is something that has already been tested and proven safe. However, more research is needed on the drug and the various molecular mechanisms it acts on to prevent aging

.

Despite everything, experts insist that consumption metformin You should always consult a specialist as side effects may occur. Some are gastrointestinal problems such as nausea, vomiting and intestinal pain, or fatigue and anemia due to decreased levels B12.