After treatment with growth hormones carried out between 1959 and 1985. corpsesThe researchers found that 5 patients developed symptoms of dementia Related to Alzheimer’s disease.
What is it about first transmission of Alzheimer’s disease and what precautions the authors of the British study suggest.
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A recent study from University College London, UK, published in the journal rEvista Nature Medicine
first demonstrated random transmission protein linked to Alzheimer’s disease through Medical treatment.
This disease, associated with old age or, to a lesser extent, with genetic factors, is currently associated with direct link using a specific medical procedure.
According to this study, at least 5 patients previously exposed treatment with contaminated growth hormonewho have developed Alzheimer’s disease despite not having the appropriate age or associated genetic inheritance.
These would be first things to do Accidental transmission of the disease is popular.
growth hormone c-hGH, obtained from the pituitary (brain) glands of cadavers and used between 1959 and 1985 to treat growth problems in minors, had amyloid beta proteinand its accumulation in the brain is responsible for development Alzheimer’s disease.
hormone It was completed by 1,848 girls and boys in the United Kingdom.
The discontinuation of this treatment in 1985 was due to the presence infectious proteins which cause Creutzfeldt-Jakob disease, a brain disease that often leads to dementia.
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After it was demonstrated that growth hormones originating from the deceased were infected beta amyloidthe researchers of the said study concluded that they can still cause the accumulation of this protein in the brain.
Between 2017 and 2018, these samples were analyzed where they were found presence of beta amyloidand injected into mice. As a result, laboratory animals developed Alzheimer’s disease.
Based on this, the researchers asked themselves what would be evolution
those children who received treatment 30 years ago.Neurosurgeon John Collinge, one of the study’s authors, said it was previously thought that people exposed to this type of a growth hormone could develop Alzheimer’s disease through time without succumbing to that time Creutzfeldt-Jakob disease.
As already mentioned, the report focused on describing that of the 8 cases, 5 developed symptoms of dementia Related to Alzheimer’s disease or they meet clinical diagnostic criteria at a very young age: 38 to 55 years, which is unusual for this age and without inherited genetic variants.
For this reason, researchers emphasize the importance take extreme precautions to avoid accidental transmission of this brain disease during medical procedures.
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